Invention Grant
- Patent Title: Spiro substituted compounds as angiogenesis inhibitors
- Patent Title (中): 螺环取代的化合物作为血管发生抑制剂
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Application No.: US12036244Application Date: 2008-02-23
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Publication No.: US08148532B2Publication Date: 2012-04-03
- Inventor: Guoqing Paul Chen
- Applicant: Guoqing Paul Chen
- Main IPC: C07D215/38
- IPC: C07D215/38
Abstract:
The present invention relates to compound of Formula I, processes for their preparation, pharmaceutical compositions containing them as active ingredient, methods for the treatment of disease states associated with angiogenesis, such as cancers associated with protein tyrosine kinases, to their use as medicaments for use in the production of inhibition of tyrosine kinases reducing effects in warm-blooded animals such as humans.
Public/Granted literature
- US20080227811A1 Spiro Substituted Compounds As Angiogenesis Inhibitors Public/Granted day:2008-09-18
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