Invention Grant
US08148599B2 Transgenic non-human animals for pharmacological and toxicological studies
有权
用于药物和毒理学研究的转基因非人动物
- Patent Title: Transgenic non-human animals for pharmacological and toxicological studies
- Patent Title (中): 用于药物和毒理学研究的转基因非人动物
-
Application No.: US12860797Application Date: 2010-08-20
-
Publication No.: US08148599B2Publication Date: 2012-04-03
- Inventor: John Michael Daly
- Applicant: John Michael Daly
- Applicant Address: AU Western Australia
- Assignee: Gene Stream Pty Limited
- Current Assignee: Gene Stream Pty Limited
- Current Assignee Address: AU Western Australia
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Priority: AUPR4467 20010418
- Main IPC: G01N3/00
- IPC: G01N3/00 ; A01K67/00 ; A01K67/027
Abstract:
The present invention is directed to the production, breeding and use of transgenic non-human animals such as mice in which specific genes or portions of genes have been replaced by homologues from another animal to make the physiology of the animals so modified more like that of the other animal with respect to drug pharmacokinetics and metabolism. The invention also extends to the use of the genetically modified non-human animals of the invention for pharmacological and/or toxicological studies.
Public/Granted literature
- US20100319076A1 TRANSGENIC NON-HUMAN ANIMALS FOR PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES Public/Granted day:2010-12-16
Information query
