A filter cartridge is provided which comprises a media pack, a preform and a molded-in-place region of seal material. The media pack generally comprises a coiled arrangement of facing sheet secured to corrugated sheet. The preform includes a projection surrounding the media pack; the projection surrounding the media pack including a portion directed radially away from the media pack. The molded-in-place region of seal material defines: a radially outwardly directed surface defining a housing radial seal; and, has a portion with the projection of the preform that is directed radially away from the media pack embedded therein.