Invention Grant
- Patent Title: CD20 binding molecules
- Patent Title (中): CD20结合分子
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Application No.: US10553938Application Date: 2004-05-20
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Publication No.: US08153125B2Publication Date: 2012-04-10
- Inventor: Jeffry D. Watkins , Julian Davies , David M. Marquis , Barrett W Allan , Brian Ondek
- Applicant: Jeffry D. Watkins , Julian Davies , David M. Marquis , Barrett W Allan , Brian Ondek
- Applicant Address: US CA San Diego
- Assignee: Applied Molecular Evolution, Inc.
- Current Assignee: Applied Molecular Evolution, Inc.
- Current Assignee Address: US CA San Diego
- Agent Robert L. Sharp; Paula K. Davis
- International Application: PCT/US2004/015786 WO 20040520
- International Announcement: WO2004/103404 WO 20041202
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; C07K16/30
Abstract:
The present invention relates to CD20 binding molecules and nucleic acid sequences encoding CD20 binding molecules. In particular, the present invention relates to CD20 binding molecules with a high binding affinity, and a low dissociation rate, with regard to human CD20. Preferably, the CD20 binding molecules of the present invention comprise light and/or heavy chain variable regions with fully human frameworks (e.g. human germline frameworks).
Public/Granted literature
- US20060251652A1 Cd20 binding molecules Public/Granted day:2006-11-09
Information query
