Invention Grant
US08153153B1 Pharmaceutical composition of nanoparticles for protein drug delivery
有权
用于蛋白质药物递送的纳米颗粒药物组成
- Patent Title: Pharmaceutical composition of nanoparticles for protein drug delivery
- Patent Title (中): 用于蛋白质药物递送的纳米颗粒药物组成
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Application No.: US13134798Application Date: 2011-06-17
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Publication No.: US08153153B1Publication Date: 2012-04-10
- Inventor: Hsing-Wen Sung , Kiran Sonaje , Hosheng Tu
- Applicant: Hsing-Wen Sung , Kiran Sonaje , Hosheng Tu
- Applicant Address: US CA Newport Beach TW Hsinchu
- Assignee: GP Medical, Inc.,National Tsing Hua University
- Current Assignee: GP Medical, Inc.,National Tsing Hua University
- Current Assignee Address: US CA Newport Beach TW Hsinchu
- Main IPC: A61K9/54
- IPC: A61K9/54 ; A61K9/20
Abstract:
The invention discloses nanoparticles composed of chitosan, poly-glutamic acid, and at least one bioactive agent, wherein equal moles of the positively charged chitosan and the negatively charged poly-glutamic acid substrate form an electrostatic network with zero surface charge enabling improved loading the bioactive agent.
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