Invention Grant
- Patent Title: Hydrogel nanocompsites for ophthalmic applications
- Patent Title (中): 用于眼科应用的水凝胶纳米复合体
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Application No.: US10574667Application Date: 2004-09-03
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Publication No.: US08153156B2Publication Date: 2012-04-10
- Inventor: Nathan Ravi
- Applicant: Nathan Ravi
- Applicant Address: US DC Washington US MO St. Louis
- Assignee: The United States of America as Represented by the Department of Veteran Affairs,The Washington University in St. Louis
- Current Assignee: The United States of America as Represented by the Department of Veteran Affairs,The Washington University in St. Louis
- Current Assignee Address: US DC Washington US MO St. Louis
- Agency: Gorman Law Offices
- International Application: PCT/US2004/028637 WO 20040903
- International Announcement: WO2005/023331 WO 20050317
- Main IPC: A61K9/14
- IPC: A61K9/14

Abstract:
The present invention relates to reversible hydrogel systems. Particularly, the hydrogel of the present invention is made up of copolymers that can be a hydrogel when in an oxidize state and can be a solution when in a reduced state. A solution of the copolymer can be oxidized to form a hydrogel; and the hydrogel can be reduced to form a solution of the copolymer. Reversible nanogels can also be formed from a dilute solution of the copolymers. The hydrogel is formed with nanoparticles embedded therein to form a nanocomposite whose refractive index and modulus can be controlled by varying the amounts of nanoparticles and the polymer concentration of the hydrogel, respectively.
Public/Granted literature
- US20070269488A1 Hydrogel Nanocompsites for Ophthalmic Applications Public/Granted day:2007-11-22
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