Invention Grant
US08153386B2 Human T2R64 taste receptor and related assays for identifying human bitter taste modulators
有权
人T2R64味觉受体和用于鉴定人类苦味调节剂的相关测定法
- Patent Title: Human T2R64 taste receptor and related assays for identifying human bitter taste modulators
- Patent Title (中): 人T2R64味觉受体和用于鉴定人类苦味调节剂的相关测定法
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Application No.: US11599318Application Date: 2006-11-15
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Publication No.: US08153386B2Publication Date: 2012-04-10
- Inventor: Jon Elliot Adler
- Applicant: Jon Elliot Adler
- Applicant Address: US CA San Diego
- Assignee: Senomyx, Inc.
- Current Assignee: Senomyx, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Hunton & Williams LLP
- Main IPC: G01N33/567
- IPC: G01N33/567 ; C07K14/705 ; C12N15/12
Abstract:
The present invention relates to the discovery of a specific human taste receptor in the T2R taste receptor family, hT2R64 that responds to particular bitter compounds The present invention further relates to the use of this receptor in assays for identifying ligands that modulate the activation of this taste receptor. These compounds may be used as additives and/or removed from foods, beverages and medicinals in order to modify (block) T2R-associated bitter taste. A preferred embodiment is the use of the identified compounds as additives in foods, beverages and medicinals for blocking bitter taste.
Public/Granted literature
- US20070061902A1 Human T2R64 taste receptor and related assays for identifying human bitter taste modulators Public/Granted day:2007-03-15
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