Invention Grant
US08153645B2 Treating pain using selective antagonists of persistent sodium current
有权
使用持续钠电流的选择性拮抗剂治疗疼痛
- Patent Title: Treating pain using selective antagonists of persistent sodium current
- Patent Title (中): 使用持续钠电流的选择性拮抗剂治疗疼痛
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Application No.: US11461516Application Date: 2006-08-01
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Publication No.: US08153645B2Publication Date: 2012-04-10
- Inventor: George R. Ehring , Joseph S. Adorante , John E. Donello , Larry A. Wheeler , Thomas Malone
- Applicant: George R. Ehring , Joseph S. Adorante , John E. Donello , Larry A. Wheeler , Thomas Malone
- Applicant Address: US CA Irvine
- Assignee: Allergan, Inc.
- Current Assignee: Allergan, Inc.
- Current Assignee Address: US CA Irvine
- Agent Joel B. German; Krishna G. Banerjee
- Main IPC: A01N43/40
- IPC: A01N43/40 ; A01N43/82 ; A61K31/435 ; A61K31/44 ; A61K31/41
Abstract:
The present invention provides methods of treating chronic pain in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.
Public/Granted literature
- US20060287366A1 TREATING PAIN USING SELECTIVE ANTAGONISTS OF PERSISTENT SODIUM CURRENT Public/Granted day:2006-12-21
Information query
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