Invention Grant
US08153789B2 Imidazo[1,2-b]pyridazines, processes, uses, intermediates and compositions
有权
咪唑并[1,2-b]哒嗪，方法，用途，中间体和组合物
![Imidazo[1,2-b]pyridazines, processes, uses, intermediates and compositions](/docs/US/2012-04-10/US08153789B2/abs.jpg.600x600.jpg)
- Patent Title: Imidazo[1,2-b]pyridazines, processes, uses, intermediates and compositions
- Patent Title (中): 咪唑并[1,2-b]哒嗪，方法，用途，中间体和组合物
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Application No.: US12225740Application Date: 2007-03-28
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Publication No.: US08153789B2Publication Date: 2012-04-10
- Inventor: José Luís Falcó , Albert Palomer , Antonio Guglietta
- Applicant: José Luís Falcó , Albert Palomer , Antonio Guglietta
- Applicant Address: ES Barcelona
- Assignee: Ferrer Internacional, S.A.
- Current Assignee: Ferrer Internacional, S.A.
- Current Assignee Address: ES Barcelona
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: EP06111899 20060329
- International Application: PCT/EP2007/052988 WO 20070328
- International Announcement: WO2007/110437 WO 20071004
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61P25/20 ; A61P25/22 ; A61P25/08
![Imidazo[1,2-b]pyridazines, processes, uses, intermediates and compositions](/abs-image/US/2012/04/10/US08153789B2/abs.jpg.150x150.jpg)
Abstract:
The invention provides novel imidazo[1,2-b]pyridazines of formula (I) and pharmaceutically acceptable salts, polymorphs, hydrates, tautomers, solvates and stereoisomers thereof.Compounds of formula (I) are useful for treating or preventing diseases associated with GABAA receptors modulation, anxiety, epilepsy, sleep disorders including insomnia, and for inducing sedation-hypnosis, anesthesia, sleep and muscle relaxation.The invention also provides synthetic procedures for preparing said compounds and certain intermediates, as well as intermediates themselves.
Public/Granted literature
- US20090176788A1 Imidazo[1,2-B]Pyridazines, Processes, Uses, Intermediates and Compositions Public/Granted day:2009-07-09
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