Invention Grant
- Patent Title: Compositions and methods for modulating sirtuin activity
- Patent Title (中): 调节sirtuin活性的组合物和方法
-
Application No.: US12143478Application Date: 2008-06-20
-
Publication No.: US08153803B2Publication Date: 2012-04-10
- Inventor: Aleksey G. Kazantsev
- Applicant: Aleksey G. Kazantsev
- Applicant Address: US MA Boston
- Assignee: The General Hospital Corporation
- Current Assignee: The General Hospital Corporation
- Current Assignee Address: US MA Boston
- Agency: Nixon Peabody LLP
- Agent David S. Resnick; Leena H. Karttunen Contarino
- Main IPC: C07D215/38
- IPC: C07D215/38
Abstract:
The present invention is based, in part, on our discovery of compounds that inhibit an activity of a sirtuin (e.g., compounds that inhibit or preferentially inhibit an activity of SIRT2) and are therefore believed useful in the treatment or prevention of diseases associated with sirtuin activity. These diseases include, but are not limited to, neurological disorders such as Parkinson's Disease (PD).
Public/Granted literature
- US20090259044A1 COMPOSITIONS AND METHODS FOR MODULATING SIRTUIN ACTIVITY Public/Granted day:2009-10-15
Information query
