Invention Grant
- Patent Title: Dihydropyridone amides as P2X7 modulators
- Patent Title (中): 二氢吡啶酮酰胺作为P2X7调节剂
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Application No.: US12637520Application Date: 2009-12-14
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Publication No.: US08153808B2Publication Date: 2012-04-10
- Inventor: Francisco Javier Lopez-Tapia , Keith Adrian Murray Walker , Shu-Hai Zhao
- Applicant: Francisco Javier Lopez-Tapia , Keith Adrian Murray Walker , Shu-Hai Zhao
- Applicant Address: US CA Palo Alto
- Assignee: Roche Palo Alto LLC
- Current Assignee: Roche Palo Alto LLC
- Current Assignee Address: US CA Palo Alto
- Agent Robert C. Hall
- Main IPC: C07D211/72
- IPC: C07D211/72 ; A61K31/44
Abstract:
Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with the P2X7 purinergic receptor.
Public/Granted literature
- US20100160387A1 DIHYDROPYRIDONE AMIDES AS P2X7 MODULATORS Public/Granted day:2010-06-24
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