Invention Grant
- Patent Title: Dihydropyridone ureas as P2X7 modulators
- Patent Title (中): 二氢吡啶酮脲作为P2X7调节剂
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Application No.: US12637903Application Date: 2009-12-15
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Publication No.: US08153809B2Publication Date: 2012-04-10
- Inventor: Christine E. Brotherton-Pleiss , Joan Marie Caroon , Francisco Javier Lopez-Tapia , Dov Nitzan , Keith Adrian Murray Walker
- Applicant: Christine E. Brotherton-Pleiss , Joan Marie Caroon , Francisco Javier Lopez-Tapia , Dov Nitzan , Keith Adrian Murray Walker
- Applicant Address: US CA Palo Alto
- Assignee: Roche Palo Alto LLC
- Current Assignee: Roche Palo Alto LLC
- Current Assignee Address: US CA Palo Alto
- Agent Robert C. Hall
- Main IPC: C07D213/62
- IPC: C07D213/62 ; A61K31/44
Abstract:
Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with the P2X7 purinergic receptor.
Public/Granted literature
- US20100160388A1 DIHYDROPYRIDONE UREAS AS P2X7 MODULATORS Public/Granted day:2010-06-24
Information query
