Invention Grant
- Patent Title: Sale of fluorescent transgenic ornamental fish
- Patent Title (中): 销售荧光转基因观赏鱼
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Application No.: US11749032Application Date: 2007-05-15
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Publication No.: US08153858B2Publication Date: 2012-04-10
- Inventor: Zhiyuan Gong , Jiangyan He , Bensheng Ju , Toong Jin Lam , Yanfei Xu , Tie Yan
- Applicant: Zhiyuan Gong , Jiangyan He , Bensheng Ju , Toong Jin Lam , Yanfei Xu , Tie Yan
- Applicant Address: SG Singapore
- Assignee: National University of Singapore
- Current Assignee: National University of Singapore
- Current Assignee Address: SG Singapore
- Agency: Fulbright & Jaworski L.L.P.
- Priority: SG9900811-2 19990218; SG9903367-2 19990714
- Main IPC: A01K67/027
- IPC: A01K67/027

Abstract:
Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed respectively, were isolated and ligated to the 5′ end of the EGFP gene. When the resulting chimeric gene constructs were introduced into zebrafish, the transgenic zebrafish emit green fluorescence under a blue light or ultraviolet light according to the specificity of the promoters used. Thus, new varieties of ornamental fish of different fluorescence patterns, e.g., skin fluorescence, muscle fluorescence, skeletal muscle-specific and/or ubiquitous fluorescence, are developed.
Public/Granted literature
- US20080052787A1 Chimeric gene constructs for generation of fluorescent transgenic ornamental fish Public/Granted day:2008-02-28
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