In a method for controlling a fuel supply system of an internal combustion engine with at least one combustion chamber, into which fuel can be injected via a fuel injector, the fuel injector being activated for the implementation of a normal start-up with specified injection parameters when the fuel supply system is filled, the specified injection parameters are modified for the acceleration of an initial start-up of the internal combustion engine when a filling of the fuel supply system with fuel has been implemented to evacuate the air from said fuel supply system.