Invention Grant
US08163282B2 Monoclonal antibody capable of binding to heparin-binding epidermal growth factor-like growth factor
失效
能够结合肝素结合表皮生长因子样生长因子的单克隆抗体
- Patent Title: Monoclonal antibody capable of binding to heparin-binding epidermal growth factor-like growth factor
- Patent Title (中): 能够结合肝素结合表皮生长因子样生长因子的单克隆抗体
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Application No.: US12609434Application Date: 2009-10-30
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Publication No.: US08163282B2Publication Date: 2012-04-24
- Inventor: Eisuke Mekada , Ryo Iwamoto , Shingo Miyamoto , Kenya Shitara , Akiko Furuya , Kazuyasu Nakamura , Kumiko Takahashi , Hiroshi Ando , Kazuhiro Masuda , Yuka Sasaki
- Applicant: Eisuke Mekada , Ryo Iwamoto , Shingo Miyamoto , Kenya Shitara , Akiko Furuya , Kazuyasu Nakamura , Kumiko Takahashi , Hiroshi Ando , Kazuhiro Masuda , Yuka Sasaki
- Applicant Address: JP Tokyo
- Assignee: Kyowa Hakko Kirin Co., Ltd
- Current Assignee: Kyowa Hakko Kirin Co., Ltd
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2007-315068 20071205
- Main IPC: C07K16/00
- IPC: C07K16/00
Abstract:
Medicaments for treating diseases related to HB-EGF escalation are in demand. The present invention provides a monoclonal antibody or an antibody fragment thereof which binds to a cell membrane-bound HB-EGF, a membrane type HB-EGF and a secretory HB-EGF.
Public/Granted literature
- US20110034673A1 MONOCLONAL ANTIBODY CAPABLE OF BINDING TO HEPARIN-BINDING EPIDERMAL GROWTH FACTOR-LIKE GROWTH FACTOR Public/Granted day:2011-02-10
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