Invention Grant
- Patent Title: Methods of treating TSLP-related inflammatory disorders
- Patent Title (中): 治疗TSLP相关性炎症性疾病的方法
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Application No.: US13185021Application Date: 2011-07-18
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Publication No.: US08163284B2Publication Date: 2012-04-24
- Inventor: Michael R Comeau , James F Smothers , Bo-Rin P Yoon , Christopher Mehlin
- Applicant: Michael R Comeau , James F Smothers , Bo-Rin P Yoon , Christopher Mehlin
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Thomas J. Wrona
- Main IPC: A61K39/00
- IPC: A61K39/00

Abstract:
The present disclosure provides compositions and methods relating to antigen binding proteins which bind to human thymic stromal lymphopoietin (TSLP), including antibodies. In particular embodiments, the disclosure provides fully human, humanized and chimeric anti-TSLP antibodies and derivatives of such antibodies. The disclosure further provides nucleic acids encoding such antibodies and antibody fragments and derivatives, and methods of making and using such antibodies including methods of treating and preventing TSLP-related inflammatory and fibrotic disorders.
Public/Granted literature
- US20110274687A1 METHODS OF TREATING TSLP-RELATED INFLAMMATORY DISORDERS Public/Granted day:2011-11-10
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