Invention Grant
- Patent Title: Pyrazoles
- Patent Title (中): 吡唑
-
Application No.: US12768770Application Date: 2010-04-28
-
Publication No.: US08163728B2Publication Date: 2012-04-24
- Inventor: Roland Jakob-Roetne , Matthew C. Lucas , Andrew Thomas
- Applicant: Roland Jakob-Roetne , Matthew C. Lucas , Andrew Thomas
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- Priority: EP09159364 20090505
- Main IPC: A61K31/422
- IPC: A61K31/422 ; A61K31/541 ; A61K31/5377 ; A61K31/454 ; A61K31/4439 ; C07D417/14 ; C07D413/14 ; C07D413/12
Abstract:
The present invention is concerned with isoxazole-pyrazoles of formula I, having affinity and selectivity for GABA A α5 receptor, their manufacture, pharmaceutical compositions containing them and their use as therapeutics. The active compounds of the present invention are useful as cognitive enhancer or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.
Public/Granted literature
- US20100286115A1 PYRAZOLES Public/Granted day:2010-11-11
Information query
IPC分类:
