Invention Grant
- Patent Title: Polypeptide variants with altered effector function
- Patent Title (中): 具有改变的效应子功能的多肽变体
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Application No.: US12590801Application Date: 2009-11-12
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Publication No.: US08163882B2Publication Date: 2012-04-24
- Inventor: Leonard Presta
- Applicant: Leonard Presta
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Morrison & Foerster LLP
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08 ; A61K39/395 ; A61K39/40 ; C07K14/00
Abstract:
The present invention concerns polypeptides comprising a variant Fc region. More particularly, the present invention concerns Fc region-containing polypeptides that have altered effector function as a consequence of one or more amino acid modifications in the Fc region thereof.
Public/Granted literature
- US20100166749A1 Polypeptide variants with altered effector function Public/Granted day:2010-07-01
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