Invention Grant
- Patent Title: 4-sulfonylpiperidine derivatives
- Patent Title (中): 4-磺酰基哌啶衍生物
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Application No.: US12674999Application Date: 2008-09-12
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Publication No.: US08163898B2Publication Date: 2012-04-24
- Inventor: Tsuyoshi Nagase , Takahide Sasaki , Toshiyuki Takahashi
- Applicant: Tsuyoshi Nagase , Takahide Sasaki , Toshiyuki Takahashi
- Applicant Address: JP Tokyo
- Assignee: MSD K. K.
- Current Assignee: MSD K. K.
- Current Assignee Address: JP Tokyo
- Agent Janet E. Fair; John C. Todaro
- Priority: JP2007-244731 20070921
- International Application: PCT/JP2008/066525 WO 20080912
- International Announcement: WO2009/038021 WO 20090326
- Main IPC: C07D345/00
- IPC: C07D345/00 ; C07D517/00 ; C07D295/00 ; C07D211/60

Abstract:
[PROBLEMS]To provide compounds useful as preventives or remedies for circulatory diseases, nervous diseases, metabolic diseases, reproductive system diseases, and digestive diseases.[MEANS FOR SOLVING PROBLEMS]Compounds represented by the general formula (I) or pharmaceutically acceptable salts thereof: wherein R1 is C1-6 alkyl, C3-8 cycloalkyl, or the like; R2 is phenyl, heteroaryl, or the like; Q is N or CH; and M1, M2, M3 and M4 are each independently hydrogen or C1-6 alkyl, or alternatively M1 together with M2 or M3 forms —CH2-CH2- or the like, or M4 together with M2 or M3 forms —CH2-CH2- or the like, with the proviso that M1, M2, M3, and M4 are such that one —CH2- or —CH2-CH2- group is formed thereamong.
Public/Granted literature
- US20100234392A1 4-SULFONYLPIPERIDINE DERIVATIVES Public/Granted day:2010-09-16
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