Invention Grant
- Patent Title: Inhibitors of GLYT1 transporters
- Patent Title (中): GLYT1转运蛋白的抑制剂
-
Application No.: US11922074Application Date: 2006-06-13
-
Publication No.: US08163956B2Publication Date: 2012-04-24
- Inventor: Wesley Peter Blackaby , Ian Thomas Huscroft , Linda Elizabeth Keown , Richard Thomas Lewis , Piotr Antoni Raubo , Leslie Joseph Street , Christopher George Thomson , Joanne Thomson
- Applicant: Wesley Peter Blackaby , Ian Thomas Huscroft , Linda Elizabeth Keown , Richard Thomas Lewis , Piotr Antoni Raubo , Leslie Joseph Street , Christopher George Thomson , Joanne Thomson
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Susan L. Hess; Gerard M. Devlin
- Priority: GB0511903.7 20050613; GB0516496.7 20050811; GB0525124.4 20051212
- International Application: PCT/GB2006/002156 WO 20060613
- International Announcement: WO2006/134341 WO 20061221
- Main IPC: C07C303/00
- IPC: C07C303/00 ; C07C233/00 ; C07C237/00 ; C07C323/00 ; A61K31/16 ; A61K31/165
Abstract:
A compound of the formula (I): wherein R1, R2, R3, R4, Ar, A, n and m are defined herein, is disclosed as a GlyT1 inhibitor; pharmaceutical compositions containing the compound of the formula (I) are also disclosed as are their use in medicine, for example in the treatment of schizophrenia.
Public/Granted literature
- US20090286765A1 Therapeutic Agents Public/Granted day:2009-11-19
Information query
