An integrated circuit has operational circuitry to perform an operation. An operational regulator regulates an operating condition of the operational circuitry. The operational regulator has a sample clock to generate a sample clock signal. The sample clock signal correlates to a manufacturing variation of the electronic circuitry. The operational regulator also includes a configurator to evaluate the sample clock signal and generate a configuration signal according to the evaluation. A controller is provided to receive the configuration signal and control an operating condition of the operational circuitry according to the configuration signal.