An auto return structure of a luggage room screen may include a guide portion formed to a luggage side trim toward the rear of a vehicle body, and a reinforcement board wherein the guide portion includes a guide groove formed to the luggage side trim toward the rear of the vehicle body and slidably receiving an end portion of the reinforcement board therein, a movement groove formed to connect from ends of the lower and upper surfaces of the guide groove toward an upper part of the vehicle body to guide the end portion of the reinforcement board toward the upper part of the vehicle, and a locking protrusion formed on an upper connection portion connecting the movement groove and the upper surface of the guide groove and to which the end portion of the reinforcement board may be selectively inserted and fixed.