Invention Grant
US08168232B2 Formulations and methods of using nitric oxide mimetics in cancer treatment
有权
在癌症治疗中使用一氧化氮模拟物的制剂和方法
- Patent Title: Formulations and methods of using nitric oxide mimetics in cancer treatment
- Patent Title (中): 在癌症治疗中使用一氧化氮模拟物的制剂和方法
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Application No.: US12659124Application Date: 2010-02-25
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Publication No.: US08168232B2Publication Date: 2012-05-01
- Inventor: Charles H. Graham , Lynne-Marie Postovit , Michael A. Adams , Jeremy P. W. Heaton
- Applicant: Charles H. Graham , Lynne-Marie Postovit , Michael A. Adams , Jeremy P. W. Heaton
- Applicant Address: CA Kingston, ON
- Assignee: Queen's University at Kingston
- Current Assignee: Queen's University at Kingston
- Current Assignee Address: CA Kingston, ON
- Agency: Dowell & Dowell, PC
- Main IPC: A61K31/21
- IPC: A61K31/21 ; A61K33/00 ; A01N37/00
Abstract:
The present invention relates to methods and formulations for inhibiting, treating and preventing a malignant cell phenotype, cell, tumor and/or disease. Administration of nitric oxide mimetics, such as low doses, is sufficient to increase, restore or maintain nitric oxide-mediated signaling in cells so that malignant cell phenotypes, cells, tumors and/or diseases are inhibited or prevented. These methods and formulations are particularly useful in treating and preventing cancer in animals.
Public/Granted literature
- US20110028543A1 Formulations and methods of using nitric oxide mimetics in cancer treatment Public/Granted day:2011-02-03
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