Invention Grant
US08168387B2 Oligonucleotides, use thereof, detecting method and kit for diagnosing the presence of H5 and N1 genes of the Influenza A virus
有权
寡核苷酸，其用途，用于诊断甲型流感病毒H5和N1基因存在的检测方法和试剂盒
- Patent Title: Oligonucleotides, use thereof, detecting method and kit for diagnosing the presence of H5 and N1 genes of the Influenza A virus
- Patent Title (中): 寡核苷酸，其用途，用于诊断甲型流感病毒H5和N1基因存在的检测方法和试剂盒
-
Application No.: US12084704Application Date: 2006-11-23
-
Publication No.: US08168387B2Publication Date: 2012-05-01
- Inventor: Aurélie Lefeuvre , Jean-Noel Telles , Guy Vernet
- Applicant: Aurélie Lefeuvre , Jean-Noel Telles , Guy Vernet
- Applicant Address: FR Marcy l'Etoile
- Assignee: Biomerieux
- Current Assignee: Biomerieux
- Current Assignee Address: FR Marcy l'Etoile
- Agency: Oliff & Berridge, PLC
- Priority: FR0511974 20051125; FR0600843 20060130
- International Application: PCT/FR2006/051218 WO 20061123
- International Announcement: WO2007/060366 WO 20070531
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H21/04
Abstract:
The present invention relates to a double pair of oligonucleotides for amplifying two target sequences located, respectively, in the H5 and N1 genes of the genome of the Influenza A virus, said oligonucleotides being of a length ranging between 10 and 50 nucleotides and comprising at least one fragment of 10 consecutive nucleotides derived from the following sequences: SEQ ID No. 1:TGTATGTTGTGGAATGGCA, SEQ ID No. 2:GCCGAATGATGCCATCAA, SEQ ID No. 3:CGTGGATTGTCTCCGAAA, and SEQ ID No. 4:GGAATGCTCCTGTTATCCTGA or the sequence complementary thereto. The invention also relates to oligonucleotides for detecting amplicons, to the use of all these sequences, and to a method for detecting and a kit for diagnosing the presence of the H5 and N1 genes of the Influenza A virus.The invention is particularly applicable in the field of diagnosis.
Public/Granted literature
Information query
