Invention Grant
US08168422B2 Microorganism producing inosine and method of producing inosine using the same
有权
生产肌苷的微生物及使用其产生肌苷的方法
- Patent Title: Microorganism producing inosine and method of producing inosine using the same
- Patent Title (中): 生产肌苷的微生物及使用其产生肌苷的方法
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Application No.: US12522004Application Date: 2008-01-15
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Publication No.: US08168422B2Publication Date: 2012-05-01
- Inventor: Young-hoon Park , Kwang-myung Cho , Hee-jong Lee , Jin-nam Lee
- Applicant: Young-hoon Park , Kwang-myung Cho , Hee-jong Lee , Jin-nam Lee
- Applicant Address: KR Seoul
- Assignee: CJ Cheiljedang Corporation
- Current Assignee: CJ Cheiljedang Corporation
- Current Assignee Address: KR Seoul
- Agency: Swanson & Bratschun, L.L.C.
- Priority: KR10-2007-0004341 20070115
- International Application: PCT/KR2008/000236 WO 20080115
- International Announcement: WO2008/088156 WO 20080724
- Main IPC: C12P19/40
- IPC: C12P19/40 ; C12N9/00 ; C12N1/20 ; C12N15/00 ; C07H21/04
Abstract:
The present invention relates to a microorganism producing inosine, which is one of purine nucleoside, an important material for 5′-inosinic acid synthesis, and method for producing inosine using the same. More particularly, the present invention relates to a recombinant microorganism of Corynebacterium genus producing inosine at high concentration by inactivating the gene encoding nucleoside hydrolase II and by enhancing the expression of the gene encoding 5′-nucleotidase, which still retains the characteristics of Corynebacterium ammoniagenes CJIP2401 (KCCM-10610).
Public/Granted literature
- US20100081173A1 Microorganism Producing Inosine and Method of Producing Inosine Using the Same Public/Granted day:2010-04-01
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