Invention Grant
- Patent Title: Monoclonal antibodies against claudin-18 for treatment of cancer
- Patent Title (中): 用于治疗癌症的克劳丁-18单克隆抗体
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Application No.: US12094530Application Date: 2006-11-24
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Publication No.: US08168427B2Publication Date: 2012-05-01
- Inventor: Ugur Sahin , Ozlem Tureci , Dirk Usener , Stefan Fritz , Cristoph Uherek , Gunda Brandenburg , Harald-Gerhard Geppert , Anja Kristina Schroder , Philippe Thiel
- Applicant: Ugur Sahin , Ozlem Tureci , Dirk Usener , Stefan Fritz , Cristoph Uherek , Gunda Brandenburg , Harald-Gerhard Geppert , Anja Kristina Schroder , Philippe Thiel
- Applicant Address: DE Mainz DE Mainz
- Assignee: Ganymed Pharmaceuticals AG,Johannes Gutenberg-Universitat Mainz
- Current Assignee: Ganymed Pharmaceuticals AG,Johannes Gutenberg-Universitat Mainz
- Current Assignee Address: DE Mainz DE Mainz
- Agency: McAndrews, Held & Malloy, Ltd.
- Priority: EP05025657 20051124
- International Application: PCT/EP2006/011302 WO 20061124
- International Announcement: WO2007/059997 WO 20070531
- Main IPC: C07K16/00
- IPC: C07K16/00 ; A61K39/395
Abstract:
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.
Public/Granted literature
- US20090169547A1 MONOCLONAL ANTIBODIES AGAINST CLAUDIN-18 FOR TREATMENT OF CANCER Public/Granted day:2009-07-02
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