Invention Grant
- Patent Title: Process for chromosomal integration and DNA sequence replacement in Clostridia
- Patent Title (中): 梭菌染色体整合和DNA序列置换的过程
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Application No.: US11737025Application Date: 2007-04-18
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Publication No.: US08168434B2Publication Date: 2012-05-01
- Inventor: Philippe Soucaille , Rainer Figge , Christian Croux
- Applicant: Philippe Soucaille , Rainer Figge , Christian Croux
- Applicant Address: FR Saint Beauzire
- Assignee: Metabolic Explorer
- Current Assignee: Metabolic Explorer
- Current Assignee Address: FR Saint Beauzire
- Agency: Baker Donelson Bearman Caldwell & Berkowitz, PC
- Priority: WOPCT/EP2006/066997 20061003
- Main IPC: C12N15/74
- IPC: C12N15/74 ; C12N1/21
Abstract:
The present invention is related to a new method for replacing or deleting DNA sequences in Clostridia, with high efficiency, easy to perform and applicable at an industrial level. This method is useful to modify several genetic loci in Clostridia in a routine manner. This method is based on a replicative vector carrying at least two marker genes.
Public/Granted literature
- US20080085558A1 Process for Chromosomal Integration and DNA Sequence Replacement in Clostridia Public/Granted day:2008-04-10
Information query
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