Invention Grant
- Patent Title: Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment of diabetes
- Patent Title (中): β-氨基杂环二肽基肽酶抑制剂治疗糖尿病
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Application No.: US12694758Application Date: 2010-01-27
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Publication No.: US08168637B2Publication Date: 2012-05-01
- Inventor: Scott D. Edmondson , Dooseop Kim , Malcolm Maccoss , Emma R. Parmee , Ann E. Weber , Jinyou Xu
- Applicant: Scott D. Edmondson , Dooseop Kim , Malcolm Maccoss , Emma R. Parmee , Ann E. Weber , Jinyou Xu
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Baerbel R. Brown; John C. Todaro
- Main IPC: A61K31/50
- IPC: A61K31/50 ; A61K31/35 ; A61K31/215
Abstract:
The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Public/Granted literature
- US20100130504A1 BETA-AMINO HETEROCYCLIC DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES Public/Granted day:2010-05-27
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