Invention Grant
- Patent Title: Quinazolinone derivatives as tubulin polymerization inhibitors
- Patent Title (中): 喹唑啉酮衍生物作为微管蛋白聚合抑制剂
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Application No.: US12934733Application Date: 2009-03-26
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Publication No.: US08168644B2Publication Date: 2012-05-01
- Inventor: Eddy Jean Edgard Freyne , Laurence Anne Mevellec , Jorge Eduardo Vialard , Christophe Meyer , Elisabeth Thérèse Jeanne Pasquier , Xavier Marc Bourdrez , Patrick René Angibaud
- Applicant: Eddy Jean Edgard Freyne , Laurence Anne Mevellec , Jorge Eduardo Vialard , Christophe Meyer , Elisabeth Thérèse Jeanne Pasquier , Xavier Marc Bourdrez , Patrick René Angibaud
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Priority: EP08153428 20080327
- International Application: PCT/EP2009/053604 WO 20090326
- International Announcement: WO2009/118384 WO 20091001
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/517 ; C07D239/72
Abstract:
The present invention provides compounds of formula (I), their use as inhibitors of tubulin polymerization as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, n, m and X have defined meanings.
Public/Granted literature
- US20110028433A1 QUINAZOLINONE DERIVATIVES AS TUBULIN POLYMERIZATION INHIBITORS Public/Granted day:2011-02-03
Information query
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