Invention Grant
- Patent Title: Peptide aptamers that bind to the rep proteins of ssDNA viruses
- Patent Title (中): 结合ssDNA病毒rep蛋白的肽适体
-
Application No.: US11995973Application Date: 2006-08-04
-
Publication No.: US08168748B2Publication Date: 2012-05-01
- Inventor: Linda Hanley-Bowdoin , Luisa Lopez-Ochoa
- Applicant: Linda Hanley-Bowdoin , Luisa Lopez-Ochoa
- Applicant Address: US NC Raleigh
- Assignee: North Carolina State University
- Current Assignee: North Carolina State University
- Current Assignee Address: US NC Raleigh
- Agency: Myers Bigel Sibley & Sajovec, PA
- International Application: PCT/US2006/030941 WO 20060804
- International Announcement: WO2007/019532 WO 20070215
- Main IPC: C07K7/00
- IPC: C07K7/00 ; C07K7/04 ; C07K7/08 ; A61P31/12
Abstract:
Polypeptides and fusion proteins that bind to eukaryotic viruses, in particular, eukaryotic single-stranded DNA (ssDNA) viruses are provided. The polypeptides and fusion proteins bind to the replication initiation proteins (Rep) of ssDNA viruses and optionally inhibit viral replication and/or viral infection. The virus can be a plant pathogen or animal pathogen. Consensus sequences used to identify polypeptides that bind to eukaryotic viruses are also provided.
Public/Granted literature
- US20080289065A1 Peptide Aptamers That Bind to the Rep Proteins of Ssdna Viruses Public/Granted day:2008-11-20
Information query
