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US08168750B2 Subunits of the adenovirus fiber protein and uses thereof as vaccines 有权
腺病毒纤维蛋白的亚单位及其作为疫苗的用途

Subunits of the adenovirus fiber protein and uses thereof as vaccines
Abstract:
A nucleic acid sequence encoding a fragment of the adenovirus fiber capsid protein, a DNA construct including a replicable expression vector and at least one heterologous nucleic acid, and recombinant protein including fragment of the adenovirus fiber capsid protein. The fragment comprises the C-terminal knob and part of the shaft domain of the fiber protein of these adenoviruses. The use of recombinant proteins as an active ingredient in vaccinating compositions for conferring to an animal immunity against a pathogenic infection by an adenovirus, and methods for vaccinating a domestic bird against a pathogenic adenoviral infection.
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