Invention Grant
US08168776B2 Method for making a 21 nucleotide double stranded RNA chemically linked at one end
有权
制备在一端化学连接的21个核苷酸双链RNA的方法
- Patent Title: Method for making a 21 nucleotide double stranded RNA chemically linked at one end
- Patent Title (中): 制备在一端化学连接的21个核苷酸双链RNA的方法
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Application No.: US10382768Application Date: 2003-03-06
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Publication No.: US08168776B2Publication Date: 2012-05-01
- Inventor: Roland Kreutzer , Stefan Limmer
- Applicant: Roland Kreutzer , Stefan Limmer
- Applicant Address: US MA Cambridge
- Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Fenwick & West LLP
- Priority: DE19903713 19990130; DE19956568 19991124
- Main IPC: C07H21/00
- IPC: C07H21/00 ; C07H21/04
Abstract:
The present invention provides methods and compositions for inhibiting gene expression using double stranded RNA molecules that are between 15 and 21 nucleotides in length and are complementary to a target gene sequence.
Public/Granted literature
- US20040053875A1 Method and medicament for inhibiting the expression of a given gene Public/Granted day:2004-03-18
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