Invention Grant
US08168782B2 Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and intermediates related thereto
有权
制备8-氯-1-甲基-2,3,4,5-四氢-1H-3-苯并吖庚因的方法及其相关的中间体
- Patent Title: Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and intermediates related thereto
- Patent Title (中): 制备8-氯-1-甲基-2,3,4,5-四氢-1H-3-苯并吖庚因的方法及其相关的中间体
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Application No.: US12225966Application Date: 2007-04-02
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Publication No.: US08168782B2Publication Date: 2012-05-01
- Inventor: Ulrich Weigl , Frank Porstmann , Christoph Straessler , Lars Ulmer , Ulf Koetz
- Applicant: Ulrich Weigl , Frank Porstmann , Christoph Straessler , Lars Ulmer , Ulf Koetz
- Applicant Address: US CA San Diego
- Assignee: Arena Pharmaceuticals, Inc.
- Current Assignee: Arena Pharmaceuticals, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Foley & Lardner LLP
- International Application: PCT/US2007/008170 WO 20070402
- International Announcement: WO2007/120517 WO 20071025
- Main IPC: C07D223/16
- IPC: C07D223/16
Abstract:
The present invention provides processes, methods and intermediates for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, salts, hydrates and crystal forms thereof which are useful as serotonin (5-HT) receptor agonists for the treatment of, for example, central nervous system disorders such as obesity.
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