Invention Grant
- Patent Title: Process for the preparation of imatinib and intermediates thereof
- Patent Title (中): 制备伊马替尼及其中间体的方法
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Application No.: US12515105Application Date: 2007-11-15
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Publication No.: US08168787B2Publication Date: 2012-05-01
- Inventor: Alessandro Falchi , Ennio Grendele , Riccardo Motterle , Mariano Stivanello
- Applicant: Alessandro Falchi , Ennio Grendele , Riccardo Motterle , Mariano Stivanello
- Applicant Address: IT Alte di Montecchio Maggiore, Vicenza
- Assignee: F.I.S. Fabbrica Italiana Sintetici S.p.A.
- Current Assignee: F.I.S. Fabbrica Italiana Sintetici S.p.A.
- Current Assignee Address: IT Alte di Montecchio Maggiore, Vicenza
- Agency: Dickstein Shapiro LLP
- Priority: ITMI2006A002208 20061116; ITMI2007A000942 20070509
- International Application: PCT/IT2007/000804 WO 20071115
- International Announcement: WO2008/059551 WO 20080522
- Main IPC: C07D401/04
- IPC: C07D401/04
Abstract:
A process for the preparation of 4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-benzenediamine and analogues thereof, intermediates useful for the synthesis of Imatinib, or 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide.
Public/Granted literature
- US20100076189A1 PROCESS FOR THE PREPARATION OF IMATINIB AND INTERMEDIATES THEREOF Public/Granted day:2010-03-25
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