Invention Grant
US08168797B2 Oxazolidinone derivative with difluorophenyl moiety, pharmaceutically acceptable salt thereof, preparation method thereof and antibiotic composition containing the same as an active ingredient
有权
具有二氟苯基部分的恶唑烷酮衍生物，其药学上可接受的盐，其制备方法和含有其作为活性成分的抗生素组合物
- Patent Title: Oxazolidinone derivative with difluorophenyl moiety, pharmaceutically acceptable salt thereof, preparation method thereof and antibiotic composition containing the same as an active ingredient
- Patent Title (中): 具有二氟苯基部分的恶唑烷酮衍生物，其药学上可接受的盐，其制备方法和含有其作为活性成分的抗生素组合物
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Application No.: US12277364Application Date: 2008-11-25
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Publication No.: US08168797B2Publication Date: 2012-05-01
- Inventor: Chang Hyun Oh , Jung Hyuck Cho
- Applicant: Chang Hyun Oh , Jung Hyuck Cho
- Applicant Address: KR Seoul
- Assignee: Korea Institute of Science and Technology
- Current Assignee: Korea Institute of Science and Technology
- Current Assignee Address: KR Seoul
- Agency: Ladas & Parry LLP
- Priority: KR10-2008-0090659 20080916
- Main IPC: C07D413/00
- IPC: C07D413/00 ; C07D263/00 ; A61K31/42 ; A61K31/421
Abstract:
Novel oxazolidinone derivatives with a difluorophenyl moiety, represented by Chemical Formula 1, pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition containing the same as an active ingredient are provided. Exhibiting potent inhibitory activity against Gram-positive bacteria including Haemophilus influenza and Coagulase negative staphylococci and resistant bacteria including vancomycin-resistant enterococci (VRE), the pharmaceutical composition is useful as an antibiotic (wherein, R is as defined in the specification).
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