A web product folding and stacking machine includes two folding line making wheels, two folding fingers, a first carrier unit, a stoppage unit and a holder. The folding line making wheels and the folding fingers are operated to fold up web products on the first carrier unit to form a stack of interfolded web products. When a stack of a predetermined number of interfolded web products is finished, the stoppage unit is extended out to isolate the interfolded web products. Further, a retractable member of the stoppage unit is extended out to hold down the finished stack of interfolded web products when the stoppage unit is lowered to carry the finished stack of interfolded web products with the holder, keeping the finished stack of interfolded web products in integrity.