Invention Grant
- Patent Title: Medical devices having antimicrobial coatings thereon
- Patent Title (中): 在其上具有抗微生物涂层的医疗装置
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Application No.: US10722256Application Date: 2003-11-25
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Publication No.: US08172395B2Publication Date: 2012-05-08
- Inventor: Fiona Patricia Carney , Manal M. Gabriel , Carol Ann Morris , John Martin Lally
- Applicant: Fiona Patricia Carney , Manal M. Gabriel , Carol Ann Morris , John Martin Lally
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Sheng-Hsin Hu; Jian Zhou
- Main IPC: G02C7/02
- IPC: G02C7/02

Abstract:
The present invention provides a medical device, preferably a contact lens, which comprises an antimicrobial LbL coating containing one or more antimicrobial pepetides. The antimicrobial coating of the invention can impart to the medical an increased surface hydrophilicity and a relatively high antimicrobial activity coupled with low cytotoxicity. The antimicrobial coating of the invention has a minimal adverse effects on the desirable bulk properties of a contact lens, such as oxygen permeability, ion permeability, and optical properties. An antimicrobial coating of the present invention may find particular use in extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial LbL coating thereon.
Public/Granted literature
- US20040135967A1 Medical devices having antimicrobial coatings thereon Public/Granted day:2004-07-15
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