A system and method are provided for performing a simulation of patient treatment using at least one executable clinical guideline. The method includes the steps of: providing for getting a selected start point associated with a step of a guideline, wherein the start point is selectable regardless of the actual treatment provided to the patient and condition of the patient; providing for accessing a guideline associated with the start point; and providing for performing a simulation. The simulation includes the steps of providing for processing the start point; providing for accessing the guideline having the step associated with the start point; and providing for executing at least the associated guideline including beginning execution at the start point.