A dumbbell having an antimicrobial handle comprises a bar having a pair of end regions, and extending generally longitudinally therebetween along a generally central axis, weight plate masses mounted at the end regions and mechanically secured thereto, and a pair of collars located at longitudinally opposed positions on bar to define a handle region therebetween. A handle is located within the handle region and includes a generally tubular grip surface member supported by the bar and formed from an antimicrobial copper alloy, the generally tubular grip surface member extending generally axially between longitudinally spaced-apart end regions. The pair of longitudinally-spaced generally annular collars have axially-inwardly extending flange portions sized and structured to substantially circumscribe the end regions of the generally cylindrical grip surface member and to securely capture the end regions between the flange portions and the bar.