The present disclosure is generally directed to centrifuge systems and methods for controlling centrifuge systems, wherein the systems in certain aspects are adapted for processing material, e.g., but not limited to drilling fluids with solids therein. One illustrative method includes providing a centrifuge system that is made up of, among other things, a bowl, a bowl motor system, a bowl variable frequency drive, a conveyor, a conveyor motor, a conveyor variable frequency drive, a pump, a pump motor, and a pump variable frequency drive. Additionally, the centrifuge system includes a control system that is adapted to control the bowl variable frequency drive, the conveyor variable frequency drive, and the pump variable frequency drive. The method includes controlling the centrifuge system in the G-force differential control mode by controlling the G-force on the bowl as the bowl is rotated by the bowl motor system so that the G-force on the bowl does not exceed a pre-set maximum G-force.