A ligation clip applicator design is provided that is particularly applicable to placement of a surgical ligation clip during a laparoscopic surgical procedure. The applicator has a magazine including first and second longitudinally extending partially closed channels within which enlarged portions of a ligation clip are received and held in an open position. First and second substantially parallel compression members are attached to the magazine and have first and second channel extensions therein aligned with the first and second channels of the magazine for receiving the first and second enlarged portions of the clip. The channel extensions include first and second releasing openings. The compression members close about a vessel, remaining substantially parallel as they close. The clip is pushed forward into the compression members to a position where the enlarged portions of the clip are aligned with the releasing openings, permitting the clip to be released to close and ligate the vessel.