Invention Grant
US08173104B2 Controlled-release immunogenic formulations to modulate immune response
有权
控制释放免疫原性制剂以调节免疫反应
- Patent Title: Controlled-release immunogenic formulations to modulate immune response
- Patent Title (中): 控制释放免疫原性制剂以调节免疫反应
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Application No.: US12554282Application Date: 2009-09-04
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Publication No.: US08173104B2Publication Date: 2012-05-08
- Inventor: Matthew J. Kipper , Balaji Narasimhan , Jennifer H. Wilson , Michael J. Wannemuehler
- Applicant: Matthew J. Kipper , Balaji Narasimhan , Jennifer H. Wilson , Michael J. Wannemuehler
- Applicant Address: US IA Ames
- Assignee: Iowa State University Research Foundation, Inc.
- Current Assignee: Iowa State University Research Foundation, Inc.
- Current Assignee Address: US IA Ames
- Agency: Schwegman, Lundberg & Woessner, P.A.
- Main IPC: A61K49/00
- IPC: A61K49/00 ; A61K39/00 ; A61K39/02
Abstract:
Single-dose controlled-release immunogenic formulations, such as vaccines, based on bioerodible polyanhydride copolymer or homopolymer microparticles for the control of immune response mechanisms are provided. The copolymer or homopolymer microparticles degrade by surface-erosion from in vivo hydrolysis of anhydride linkages at the surface of the microparticle, which results in controlled release of immunogen(s) to a patient.
Public/Granted literature
- US20100021546A1 CONTROLLED-RELEASE IMMUNOGENIC FORMULATIONS TO MODULATE IMMUNE RESPONSE Public/Granted day:2010-01-28
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