Invention Grant
US08173118B2 Compositions consisting essentially of TGF-β, BMP-2 FGF-4, leukemia inhibitory factor, IGF-1, IL-6 and H-α-thrombin
有权
基本上由TGF-β1,BMP-2FGF-4,白血病抑制因子,IGF-1,IL-6和H-α-凝血酶组成的组合物
- Patent Title: Compositions consisting essentially of TGF-β, BMP-2 FGF-4, leukemia inhibitory factor, IGF-1, IL-6 and H-α-thrombin
- Patent Title (中): 基本上由TGF-β1,BMP-2FGF-4,白血病抑制因子,IGF-1,IL-6和H-α-凝血酶组成的组合物
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Application No.: US11572874Application Date: 2005-07-29
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Publication No.: US08173118B2Publication Date: 2012-05-08
- Inventor: Andre Terzic , Atta Behfar
- Applicant: Andre Terzic , Atta Behfar
- Applicant Address: US MN Rochester
- Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee Address: US MN Rochester
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2005/026800 WO 20050729
- International Announcement: WO2006/015127 WO 20060209
- Main IPC: A61K38/18
- IPC: A61K38/18 ; A61K38/19 ; C07K14/475 ; C07K14/495 ; C07K14/50 ; C07K14/51 ; C07K14/54 ; C07K14/65 ; C07K14/745

Abstract:
This document provides methods and materials for treating cardiovascular tissue. For example, stem cells, compositions containing stem cells, methods for obtaining stem cells, compositions for generating stem cells expressing particular markers (e.g., compositions comprising TGF-β1, BMP-2, FGF-4, and leukemia inhibitory factor), and methods for repairing cardiovascular tissue are provided.
Public/Granted literature
- US20080213214A1 Treating Cardiovascular Tissue Public/Granted day:2008-09-04
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