Invention Grant
US08173127B2 Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof
有权
淀粉样蛋白β肽的特异性抗体，药物组合物及其使用方法
- Patent Title: Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof
- Patent Title (中): 淀粉样蛋白β肽的特异性抗体，药物组合物及其使用方法
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Application No.: US10084380Application Date: 2002-02-28
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Publication No.: US08173127B2Publication Date: 2012-05-08
- Inventor: Daniel G. Chain
- Applicant: Daniel G. Chain
- Applicant Address: US NC New York
- Assignee: Intellect Neurosciences, Inc.
- Current Assignee: Intellect Neurosciences, Inc.
- Current Assignee Address: US NC New York
- Agency: Fish & Richardson P.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K48/00
Abstract:
The invention relates to methods of treating a subject having Alzheimer's Disease, comprising the step of administering an antibody molecule which is targeted to β amyloid peptide or to fragment thereof. In another embodiment the invention relates to methods of treating a disease or a disorder, characterized by amyloid beta deposition. In another embodiment, the invention relates to an antibody molecule, which is free end-specific for the N-terminus or the C-terminus of an amyloid β peptide and to a pharmaceutical composition thereof. In another embodiment, the invention relates to an antibody molecule, which is targeted to the free C or N-terminus of a N-and/or C-terminus truncated amyloid β peptide fragment.
Public/Granted literature
- US20030073655A1 Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof Public/Granted day:2003-04-17
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