Invention Grant
- Patent Title: Antibodies against flagellin and uses thereof
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Application No.: US12231777Application Date: 2008-09-05
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Publication No.: US08173130B2Publication Date: 2012-05-08
- Inventor: Andrew L. Salzman , Kanneganti Murthy
- Applicant: Andrew L. Salzman , Kanneganti Murthy
- Applicant Address: US MA Lexington
- Assignee: Inotek Pharmaceuticals Corporation
- Current Assignee: Inotek Pharmaceuticals Corporation
- Current Assignee Address: US MA Lexington
- Agency: Nelson Mullins Riley Scarborough LLP
- Agent Jane E. Remillard, Esq.; Jill Gorny Sloper, Esq.
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/38 ; A61K39/40 ; A61K39/395
Abstract:
The present invention provides a novel class of monoclonal antibodies which have a high affinity, broad spectrum neutralizing reactivity to flagellin from various Gram-negative bacteria including, but not limited to, E. coli, Salmonella, Serratia, Proteus, Enterobacter, Citrobacter, Campylobacter and Pseudomonas. The present invention further provides methods of treating inflammatory bowel disease (IBD) and methods of treating enterobacterial infections using anti-flagellin antibodies in humans, other animals and birds.
Public/Granted literature
- US20090191208A1 Antibodies against flagellin and uses thereof Public/Granted day:2009-07-30
Information query
