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US08173135B2 Methods for preparing complex multivalent immunogenic conjugates 有权
制备复合多价免疫原性缀合物的方法

Methods for preparing complex multivalent immunogenic conjugates
Abstract:
Methods for preparing complex multivalent immunogenic conjugates that include simultaneously reacting a plurality or immunogenic-distinct polysaccharides with at least one protein to make the complex multivalent immunogenic conjugates. The simultaneous reaction involves reaction of a hydrazide group on one reactant with an aldehyde or cyanate ester group on the other reactant.
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