Invention Grant
- Patent Title: Method for producing porous β-tricalcium phosphate granules
- Patent Title (中): 生产多孔磷酸三钙颗粒的方法
-
Application No.: US12072105Application Date: 2008-02-21
-
Publication No.: US08173149B2Publication Date: 2012-05-08
- Inventor: Paresh S. Dalal , Godofredo R. Diamaano , Shailesh C. Kulkarni
- Applicant: Paresh S. Dalal , Godofredo R. Diamaano , Shailesh C. Kulkarni
- Applicant Address: US MI Kalamazoo
- Assignee: Stryker Corporation
- Current Assignee: Stryker Corporation
- Current Assignee Address: US MI Kalamazoo
- Agency: McCraken & Frank LLC
- Main IPC: A61F2/00
- IPC: A61F2/00 ; C12N11/14 ; C07K17/14 ; A01N37/18 ; A61K31/7088

Abstract:
A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter is in the range of 20-500 μm, preferably 50-125 μm. The porous β-TCP material provides a carrier matrix for bioactive agents and can form a moldable putty composition upon the addition of a binder. Preferably, the bioactive agent is encapsulated in a biodegradable agent. The invention provides a kit and an implant device comprising the porous β-TCP, and a bioactive agent and a binder. The invention also provides an implantable prosthetic device comprising a prosthetic implant having a surface region, a porous β-TCP material disposed on the surface region and optionally comprising at least a bioactive agent or a binder. Methods of producing the porous β-TCP material and inducing bone formation are also provided.
Public/Granted literature
- US20090110743A1 Porous beta-tricalcium phosphate granules and methods for producing same Public/Granted day:2009-04-30
Information query
IPC分类: