Invention Grant
- Patent Title: Formulation and process for the preparation of modafinil
- Patent Title (中): 莫达非尼的制备和制备方法
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Application No.: US11776012Application Date: 2007-07-11
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Publication No.: US08173169B2Publication Date: 2012-05-08
- Inventor: Mohannad Shawer , AlSayed AlArabi Sallam , Dalia Jawhari
- Applicant: Mohannad Shawer , AlSayed AlArabi Sallam , Dalia Jawhari
- Applicant Address: JO Amman
- Assignee: Hikma Pharmaceuticals
- Current Assignee: Hikma Pharmaceuticals
- Current Assignee Address: JO Amman
- Agency: Sutherland Asbill & Brennan LLP
- Main IPC: A61K9/16
- IPC: A61K9/16 ; A61K9/20 ; A61K9/48
Abstract:
The present invention provides pharmaceutical tablets comprising modafinil particles, processes for preparing such pharmaceutical tablets, and methods of treating a disease or disorder using the pharmaceutical tablet of the invention. In particular, the pharmaceutical tablet of the invention comprises modafinil particles and one or more pharmaceutically acceptable excipients, wherein the modafinil particles have a size distribution such that at least about 65% of the modafinil particles have a diameter greater than 220 microns and the tablet is bioequivalent to PROVIGIL®. The pharmaceutical tablet of the invention is prepared by a dry granulation method.
Public/Granted literature
- US20070275057A1 Formulation and Process for the Preparation of Modafinil Public/Granted day:2007-11-29
Information query
