Invention Grant
- Patent Title: Assay for cardiac troponin autoantibodies
- Patent Title (中): 测定心肌肌钙蛋白自身抗体
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Application No.: US12857615Application Date: 2010-08-17
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Publication No.: US08173382B2Publication Date: 2012-05-08
- Inventor: Phillip G. Mattingly , Maciej Adamczyk , Roy Jeffrey Brashear , Robert C. Doss
- Applicant: Phillip G. Mattingly , Maciej Adamczyk , Roy Jeffrey Brashear , Robert C. Doss
- Applicant Address: US IL Abbott Park
- Assignee: Abbott Laboratories
- Current Assignee: Abbott Laboratories
- Current Assignee Address: US IL Abbott Park
- Agency: Emily Haliday, Weaver, Austin, Villeneuve & Sampson LLP
- Agent Audrey L. Bartnicki
- Main IPC: G01N31/00
- IPC: G01N31/00 ; G01N33/53

Abstract:
The invention provides among other things methods and kits based on assaying for cardiac troponin autoantibodies, either in conjunction with an assay for cardiac troponin and/or as an independent indicator of cardiac pathology, such as myocarditis, cardiomyopathy, and/or ischemic heart disease. Assay methods of the invention can be employed among other things to identify cardiac pathology, or risk thereof, in subjects who have an autoimmune disease or who are related to an individual with an autoimmune disease. In particular embodiments, the invention also provides a method of determining whether a subject having, or at risk for, a cardiac pathology is a candidate for immunosuppressive therapy or immunoabsorption therapy. The invention also provides kits and kit components that are useful for performing the methods of the invention.
Public/Granted literature
- US20100311079A1 ASSAY FOR CARDIAC TROPONIN AUTOANTIBODIES Public/Granted day:2010-12-09
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