Invention Grant
US08173410B2 Isoprene synthase variants for improved microbial production of isoprene
有权
异戊二烯合成酶变体用于改善异戊二烯的微生物产生
- Patent Title: Isoprene synthase variants for improved microbial production of isoprene
- Patent Title (中): 异戊二烯合成酶变体用于改善异戊二烯的微生物产生
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Application No.: US12429143Application Date: 2009-04-23
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Publication No.: US08173410B2Publication Date: 2012-05-08
- Inventor: Richard R. Bott , Marguerite A. Cervin , James T. Kellis, Jr. , Joseph C. McAuliffe , Andrei Miasnikov , Caroline M. Peres , Christopher Lee Rife , Derek H. Wells , Walter Weyler , Gregory M. Whited
- Applicant: Richard R. Bott , Marguerite A. Cervin , James T. Kellis, Jr. , Joseph C. McAuliffe , Andrei Miasnikov , Caroline M. Peres , Christopher Lee Rife , Derek H. Wells , Walter Weyler , Gregory M. Whited
- Applicant Address: US CA Palo Alto
- Assignee: Danisco US Inc.
- Current Assignee: Danisco US Inc.
- Current Assignee Address: US CA Palo Alto
- Agency: Morrison & Foerster LLP
- Main IPC: C12N9/88
- IPC: C12N9/88 ; C12N15/09 ; C12N15/00 ; C12N1/20 ; C12P5/02 ; C07H21/04 ; C07K1/00
Abstract:
The present invention provides methods and compositions comprising at least one isoprene synthase enzyme with improved catalytic activity and/or solubility. In particular, the present invention provides variant plant isoprene synthases for increased isoprene production in microbial host cells. Biosynthetically produced isoprene of the present invention finds use in the manufacture of rubber and elastomers.
Public/Granted literature
- US20100003716A1 ISOPRENE SYNTHASE VARIANTS FOR IMPROVED MICROBIAL PRODUCTION OF ISOPRENE Public/Granted day:2010-01-07
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